Opinions

N.S. at crossroads coping with opiates

By DR. RONALD FRASER
An array of empty bottles of seized methadone and a vial of hydromorphone are seen at the Kentville police station in March. The bottles have the scripts from their prescriptions torn off by their illegal seller. (TIM KROCHAK / Staff / File)
Average: 3.7 (3 votes)

With another young Nova Scotian’s life cut short due to substance misuse — this time because of methadone — the topic of treating opiate dependence has been in the spotlight.

In recent days, many opinions have been shared about how to manage opiate dependence in our province. I would like to return the focus of the conversation to what the evidence tells us.

We actually know a great deal about the treatment of opiate dependence, what is effective and what is not.

We know that abstinence-based programs, though well-suited for problems such as alcohol dependence, do not work well for opiate dependence.

The most effective treatment for opiate dependence is substitution therapy — providing another opiate, such as methadone or buprenorphine, in a controlled manner.

Such programs have been shown to reduce crime, reduce death and chronic illness, and decrease the transmission of infectious diseases such as HIV and hepatitis.

People treated in such programs also experience higher rates of returning to work or school and increased quality of life.

However, simply handing out prescriptions is not enough. Ideally, an opiate treatment program should include a strong programming component involving education and therapy, helping people recover from addiction and rebuild their lives.

Best practice examples of therapies that have been shown to make a difference in supporting people’s recovery include cognitive behavioural therapy, contingency management, motivational enhancement therapy or structured relapse prevention.

When individuals die due to illicit methadone, many assume it became available as a result of a client diverting it from a treatment program.

This is not always the case. Organized crime is a major player in the illicit provision of methadone. At times, in some jurisdictions, physicians and pharmacists have been responsible for diverting narcotics.

Such physicians and pharmacists represent only a tiny minority among their profession.

Similarly, methadone patients who divert their medication represent only a small percentage of total clients served by opiate dependence treatment programs.

In fact, most clients spend years, sometimes decades, on methadone without incident.

For many of the clients in our treatment programs, methadone has been a life-saver, and often they require methadone maintenance therapy over the long term, occasionally lifelong, in order to stay well.

Having privileges to take home doses of methadone (“carry home privileges”) is part of the recovery process and represents an important step in rebuilding one’s life.

To suggest that all patients should be observed consuming their methadone every day for their entire treatment because a minority divert their methadone is an overreaction.

This would be a standard of care that does not exist anywhere else in North America.

This is not to say that we could not do a better job of monitoring and controlling opiate treatment.

I would advocate for stronger monitoring of programs and an accepted standard of care for methadone treatment, one mandated by the province.

Currently, each methadone program operates independently, with no overarching framework to ensure that, along with funding, there is accountability for the delivery of scientifically sound and medically safe programming.

The Nova Scotia College of Physicians and Surgeons recently released methadone guidelines, which were comprehensive and excellent. But what process is in place to ensure that these guidelines will be followed consistently?

For example, the guidelines recommend that any new patient be closely monitored daily for a minimum of three months before being granted “carry home” privileges, which is the standard that we will be adopting at Addiction Prevention and Treatment Services, Capital Health.

Nova Scotians deserve a provincial vision and strategic plan for how opiate treatment will be delivered safely, effectively and consistently across all health districts. Patients and their family members deserve the same level of care whether they are living in Yarmouth, Halifax or New Waterford.

Nova Scotia is at a crossroads in treating opiate dependence. We need to be proactive about this opportunity and insist that our opiate treatment programs across Nova Scotia be evidence-based, incorporate best practices and that there be accountability and oversight ensuring that individuals suffering from opiate dependence are receiving the safe, sound, optimal care that they deserve.

That is what will save lives.

Dr. Ronald Fraser, MD, CSPQ, FRCPC, is Consulting Psychiatrist, Clinical Academic Leader, Addiction Prevention and Treatment Services Capital District Health Authority, and Assistant Professor, Department of Psychiatry, Dalhousie University, McGill University.

Pain Monkeys

WOW

"In fact, most clients spend years, sometimes decades, on methadone without incident."

Decades hooked on Methadone, how is that treatment, when are they able to stop taking it?

Doesn't sound right a legal addiction to a health care related hook up on the opiates, to a lasting addiction for your life, funded via government.

I'll take the demond weed over the poppy blood any day, it may be habbit forming but it's not a cronic addiction that kills.

But i'm just a NS lab monkey for 3 decades, My Dr's are fine with me smokin demon weed as long as I don't ask them for it. Ah health care minus the care.

Decades hooked on Methadone, how is that treatment?

Pain Monkey's comments reflect a general lack of understanding shared among the general population regarding just what methadone maintenance treatment is. Part of the problem is the general terminology that is frequently employed in calling it "substitution" therapy. There is over five decades of evidence-based research behind this life-saving medication and its use in the treatment of opioid addiction and the FACTS (easily accessable via the web at the US National Institutes of Health websites) are these: Long term opioid exposure produces in the addict PERMANENT changes in brain chemistry. This lies in the endorphin system of the brain -- that which controls feelings of well-being, the ability to feel satisfaction for efforts expended in all aspects of life, the ability to have feelings of happiness and self-worth without which a life is reduced to chonic depression and feelings of failure and worthlessness. Endorphpins control all of this and the long term opioid exposed individual no longer has the ability to produce these normally. Methadone maintenance treatment should more accurately be characterized as "replacement therapy" NOT "substitution therapy." For after its ability to get the addicted individual through the withdrawal process, its long term efficacy comes from its role in "endorphin replacement," now enabling the patient to feel all of the things that mose of us take for granted that regulate our abilities to enjoy life without constant compulsion to seek equilibrium now missing permanently from our brain chemistry. This imbalance is what drives the compulsion to use opioids illicitly. It is a CHRONIC medical condition, and like all chronic conditions requires constant treatment to keep the underlying condition in remission. No different than high blood pressure or high cholesterol or diabetes. Take away the medications taken on a daily basis to control these ailments and the patient will again be out of control with the underlying condition threatening the life of the patient untreated. Opioid addiction is no different--it is a chronic condition-- one that requires endorphin replacement therapy and at this time the "gold standard" for that treatment is methadone and buprenorphine. That they are themselves addictive substances is irrelevant--they are the best modern medicine has to offer at the present time to replace this endorphin deficit. It is NOT trading one addiction for another, for addiction carries with it a particular set of behaviours that the patient no longer exhibits -- theft, inability to hold a job, loss of family relationships and on and on. They are NOT addicted, but are instead DEPENDENT on a medicine to control a chronic medical condition. I'm not addicted to my blood pressure medicine--but I'm certainly dependent upon it to keep me healthy. Same with my cholesterol medicine. The former opioid addict treated with methadone maintenance therapy is no different from those of us with these other chonic conditions. They can now "feel normal" and go about leading productive, tax paying, lives with the love of family and friends. Do we all not deserve at least this in our lives? Methadone provides that to the once addicted. Abstinance-based treatments are simply NOT EFFECTIVE in treating this underlying endorphin deficit, and their miserable rate of success in treating the opioid addict bears this out. "Replacement" treatment is needed and has saved the lives of hundreds of thousands of patients since founded by Drs. Nyswander, Dole and Volkolow back in the 1960's in the US. These are the evidence-based, scientific truths about this miracle of medicine that saves countless lives each and every day, enabling the once addicted to now go on to lead normal, productive lives as students, parents, employees and citizens. Methadone is Medicine--Methadone saves Lives! www.Methadone.org is a good place to begin to find the truths behind opioid addiction and its effective treatment.

Kind regards,
J.R. Neuberger
National Alliance for Medication Assisted Recovery (NAMA-Recovery)
"Stop Stigma Now"

ps: I have NO financial interest in this or any other type of addiction treatment method. My interest is in helping those needing these treatments in accessing that which has the best chance at giving them back the freedom and control over their lives that addiction has robbed them of. Prejudice has no role to play in any of this--only scientific evidence!

Managing opiate dependence in NovaScotia.

This article is a reminder that not everyone on opiates is abusing them and also that they provide much needed relief for those with chronic pain. It is important to monitor the use of these drugs and educate the users about the dangers of misuse. A family member that has close contact with the user should also be included in the awareness of proper use. Storage of these drugs should be considered so that they are not accessible to others entering the home.Opiates do work as pain management but should only be given after all other methods fail and when circumstances allow for responsible use and close contact with a physician.

— this time because of methadone —

No, not because of methadone, because this young woman made the choice to take this drug. With tragic consequences.

"That is what will save lives" No ,make the choice not to take these drugs, the right choice is what will save lives, not more government intervention.

Methadone is not the only solution out there

Sure methadone is a very good maintenance drug to get people with opioid dependence on a path off of these drugs, but from what I understand form people that I know that had these addictions this just switches what they are dependent on and that methadone seems harder to quit. I do think that because of it's half life that it seems to be very good for pain in terminal or long term care patients. I just think that with some of the new medications that have come on the market over the last few years seem like better treatment for addiction maintenance that fall into the opioid antagonist family of drugs. These drugs sound like a better treatment method to get patients on a road being clean. There are other things that are alternative treatments like the use of the plant Ibogaine, I have read about this one years ago and from reports that I have read it has resulted in people that have drug and alcohol addictions be free from them after a single treatment. I don't think that this one will ever catch on because of the properties of a hallucinogen that it has and with the fact that a drug company cannot make millions off of something they can sell to the public.
One of the biggest problems we have is doctors over prescribing narcotics to patients and drug stores not properly monitoring sales of OTC narcotics to the public. In someways the sale of the OTC narc's is worse on user health from the damage an excessive amount of acetaminophen has on the the liver and kidneys so they can get the amount of codeine to maintain their addiction. So when I read about an unfortunate death of a young lady from getting street drugs and outcry to go and charge the dealer for selling her the drugs should we charge a pharmacy for selling someone OTC meds that killed them?
It is a long road ahead before the problem of opioid use/abuse will be under control in our area, I know it will never be gone. I just hope that use of other medications like suboxone are investigated as treatment methods from what I know about pharmacology it sounds like it would better peoples chances for recovery



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